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Eric J Topol Selected Research

reteplase

2/2010Enoxaparin in primary and facilitated percutaneous coronary intervention A formal prospective nonrandomized substudy of the FINESSE trial (Facilitated INtervention with Enhanced Reperfusion Speed to Stop Events).
10/20091-year survival in a randomized trial of facilitated reperfusion: results from the FINESSE (Facilitated Intervention with Enhanced Reperfusion Speed to Stop Events) trial.
5/2008Facilitated PCI in patients with ST-elevation myocardial infarction.
10/2007Impact of female sex on death and bleeding after fibrinolytic treatment of myocardial infarction in GUSTO V.
10/2004ST-segment resolution 60 minutes after combination treatment of abciximab with reteplase or reteplase alone for acute myocardial infarction (30-day mortality results from the resolution of ST-segment after reperfusion therapy substudy).
11/2002Mortality at 1 year with combination platelet glycoprotein IIb/IIIa inhibition and reduced-dose fibrinolytic therapy vs conventional fibrinolytic therapy for acute myocardial infarction: GUSTO V randomized trial.

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Eric J Topol Research Topics

Disease

98Myocardial Infarction
01/2017 - 07/2001
62Hemorrhage
09/2012 - 01/2002
48Acute Coronary Syndrome
04/2012 - 07/2001
29Cardiovascular Diseases (Cardiovascular Disease)
01/2017 - 01/2002
29Stroke (Strokes)
01/2013 - 11/2002
21Thrombosis (Thrombus)
05/2012 - 02/2002
19Coronary Artery Disease (Coronary Atherosclerosis)
03/2018 - 01/2002
17Inflammation (Inflammations)
05/2021 - 02/2002
15ST Elevation Myocardial Infarction
02/2010 - 09/2002
12Atherosclerosis
03/2012 - 03/2003
12Unstable Angina
11/2009 - 07/2001
11Heart Failure
10/2014 - 01/2002
11Ischemia
02/2010 - 02/2002
11Infarction (Infarctions)
11/2008 - 02/2002
8Peripheral Arterial Disease
02/2011 - 08/2004
7Ischemic Stroke
01/2013 - 02/2004
7Vascular Diseases (Vascular Disease)
02/2011 - 07/2003
7Coronary Disease (Coronary Heart Disease)
06/2009 - 11/2003
7Vascular System Injuries
08/2005 - 10/2002
6COVID-19
04/2022 - 01/2021
6Hyperplasia
04/2006 - 04/2002
5Hypertension (High Blood Pressure)
11/2018 - 01/2002
5Diabetes Mellitus
06/2005 - 06/2002
4Atrial Fibrillation
10/2018 - 09/2003
4Neoplasms (Cancer)
01/2018 - 10/2004
4Transient Ischemic Attack
04/2012 - 05/2004
4Chronic Renal Insufficiency
05/2009 - 05/2002
3Necrosis
03/2012 - 10/2003
3Obesity
08/2010 - 04/2006
3Intracranial Hemorrhages (Intracranial Hemorrhage)
02/2010 - 02/2004
3Metabolic Syndrome (Dysmetabolic Syndrome X)
05/2008 - 12/2003
3Peripheral Vascular Diseases (Peripheral Vascular Disease)
03/2008 - 09/2003
3Anemia
11/2007 - 07/2004
3Atherosclerotic Plaque (Atheroma)
10/2007 - 03/2004
3Death (Near-Death Experience)
07/2007 - 09/2002
3Reperfusion Injury
11/2005 - 07/2002
3Myocardial Ischemia (Ischemic Heart Diseases)
10/2004 - 01/2002
2Rupture
01/2017 - 03/2003
2Cardiac Arrhythmias (Arrythmia)
01/2016 - 01/2012
2Type 2 Diabetes Mellitus (MODY)
02/2011 - 11/2005

Drug/Important Bio-Agent (IBA)

40Clopidogrel (Plavix)FDA Link
01/2013 - 01/2002
31Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2013 - 06/2002
25Abciximab (ReoPro)FDA Link
02/2010 - 01/2002
21Heparin (Liquaemin)FDA LinkGeneric
02/2010 - 04/2002
16Glycoproteins (Glycoprotein)IBA
03/2008 - 01/2002
15bivalirudin (Angiomax)FDA Link
11/2007 - 05/2002
12Platelet Membrane Glycoprotein IIbIBA
06/2006 - 12/2002
10Tirofiban (Aggrastat)FDA Link
01/2010 - 05/2002
10Platelet Membrane GlycoproteinsIBA
02/2004 - 07/2001
8Proteins (Proteins, Gene)FDA Link
10/2007 - 10/2002
8Eptifibatide (Integrilin)FDA Link
03/2005 - 07/2001
7C-Reactive ProteinIBA
10/2014 - 09/2002
7Creatine Kinase (Creatine Phosphokinase)IBA
11/2008 - 01/2002
7CreatinineIBA
11/2007 - 06/2002
7paragonIBA
10/2004 - 02/2002
6Biomarkers (Surrogate Marker)IBA
01/2018 - 02/2003
6MB Form Creatine KinaseIBA
03/2012 - 10/2003
6StreptokinaseFDA Link
03/2011 - 07/2002
6reteplaseFDA Link
02/2010 - 11/2002
6Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2008 - 02/2002
5DNA (Deoxyribonucleic Acid)IBA
03/2018 - 09/2005
5Pharmaceutical PreparationsIBA
08/2010 - 01/2002
5Peroxidase (Myeloperoxidase)IBA
10/2007 - 07/2002
4HDL CholesterolIBA
11/2018 - 12/2003
4Triglycerides (Triacylglycerol)IBA
11/2018 - 12/2003
4Biological ProductsIBA
02/2011 - 03/2003
4LipidsIBA
11/2008 - 02/2002
4CytokinesIBA
10/2006 - 03/2002
4LigandsIBA
10/2006 - 07/2002
4AntithrombinsIBA
12/2005 - 05/2002
4EnzymesIBA
10/2003 - 01/2002
4Troponin T (Troponin T1)IBA
10/2003 - 06/2002
3VaccinesIBA
04/2022 - 01/2021
3Blood Glucose (Blood Sugar)IBA
01/2016 - 11/2005
3Brain Natriuretic Peptide (Natrecor)FDA Link
10/2014 - 07/2003
3TroponinIBA
03/2012 - 02/2003
32'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
07/2011 - 07/2003
3Tissue Plasminogen Activator (Alteplase)FDA Link
10/2007 - 02/2002
3ThrombospondinsIBA
09/2007 - 06/2004
3sibrafibanIBA
06/2006 - 06/2002
3P-SelectinIBA
08/2005 - 07/2002
3Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
04/2005 - 09/2002
3AnticoagulantsIBA
11/2004 - 04/2002
2oxidized low density lipoproteinIBA
11/2018 - 06/2003
2cangrelorIBA
01/2012 - 02/2003
2Apolipoproteins E (ApoE)IBA
05/2011 - 02/2009
2EndocannabinoidsIBA
08/2010 - 01/2010
2Enoxaparin (Lovenox)FDA LinkGeneric
02/2010 - 02/2004
2Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
04/2009 - 07/2003
2tetrachloroisophthalonitrile (Bravo)IBA
11/2008 - 06/2006
2Hypoglycemic Agents (Hypoglycemics)IBA
10/2008 - 02/2004

Therapy/Procedure

57Therapeutics
10/2018 - 07/2001
43Percutaneous Coronary Intervention
09/2011 - 01/2002
20Stents
01/2012 - 01/2002
10Thrombolytic Therapy
01/2006 - 02/2002
8Coronary Artery Bypass (Coronary Artery Bypass Surgery)
05/2009 - 01/2002
4Secondary Prevention
10/2014 - 08/2003
4Blood Transfusion (Blood Transfusions)
01/2009 - 05/2004
3Ligation
11/2005 - 03/2003
2Fitness Trackers
05/2021 - 01/2021